متوکسی فلوران

Also known as Penthrane®, Methyl 1,1-difluoro-2,2-dichloroethyl ether, Methoxyfluran, Methoflurane, Methoxyfluoran, Metoxiflurano, Methoxyfluranum, Methoxyflurane

Methoxyflurane, sold under the brand name Penthrox (the "green whistle") among others, is an inhaled medication primarily used to reduce pain following an injury. It may also be used to reduce pain associated with minor medical procedures. Onset of pain relief is rapid and a standard dose typically lasts for up to 30 minutes. Use is only recommended with direct medical supervision.

Key facts

Drug.Verifiedfields: changed
Drug.Watchedfields: changed
Drug.verifiedrevid: 457473565
Drug.image: Methoxyflurane.svg
Drug.image_class: skin-invert-image
Drug.image2: Methoxyflurane-3D-balls.png
Drug.image_class2: bg-transparent
Drug.tradename: Penthrox, others
Drug.pregnancy_AU: C
Drug.routes_of_administration: Inhalation
Drug.class: Volatile anesthetic
Drug.ATC_prefix: N02
Drug.ATC_suffix: BG09
Drug.legal_AU: S4
Drug.legal_BR: C1
Drug.legal_CA: Rx-only
Drug.legal_UK: POM
Drug.legal_EU: Rx-only

via Wikipedia infobox

Chemical data

Formula: C3H4Cl2F2O
Molecular weight: 164.96 g/mol
IUPAC name: 2,2-dichloro-1,1-difluoro-1-methoxyethane
SMILES: COC(C(Cl)Cl)(F)F
InChIKey: RFKMCNOHBTXSMU-UHFFFAOYSA-N
XLogP: 2.2
Polar surface area: 9.2 Å²
H-bond donors: 0
H-bond acceptors: 3
Formal charge: 0

via PubChem

Drug data · ChEMBL

Withdrawn

Max clinical phase: Approved
Molecule type: Small molecule
Admin. routes: topical
Indications: Fever, pain, injury, cancer

via ChEMBL · EBI

Wikidata facts

Subclass of: chemical compound
Mass: 163.960727
Has use: medication

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chemical formula: C₃H₄Cl₂F₂O
boiling point: 220
Commons category: Methoxyflurane
vapor pressure: 23
lower flammable limit: 7
NIOSH Pocket Guide ID: 0389
density: 1.42
melting point: -36
ceiling exposure limit: 13.5
canonical SMILES: COC(C(Cl)Cl)(F)F
World Health Organisation international non-proprietary name: methoxyflurane
subject has role: inhalational anaesthetic
has characteristic: flammable liquid

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