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EntityQ105337735· pop 8· linked from 24 articles

Also known as PKR-IN-1, Pyrukynd, AG-348

Mitapivat, sold under the brand name Pyrukynd among others, is a medication used to treat different types of anemia. It is taken as the sulfate hydrate salt by mouth. Mitapivat is a pyruvate kinase activator.

Wikidata facts

Mass
450.172561692
Has use
medication
Show 2 more facts
canonical SMILES
C1CC1CN2CCN(CC2)C(=O)C3=CC=C(C=C3)NS(=O)(=O)C4=CC=CC5=C4N=CC=C5
chemical formula
C₂₄H₂₆N₄O₃S
Sources (2)

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Encyclopedic overview

10 sections
Contents
  • Medical uses
  • Pharmacology
  • Mechanism of action
  • History
  • Society and culture
  • Legal status
  • Names
  • References
  • Further reading
  • External links

Mitapivat, sold under the brand name Pyrukynd among others, is a medication used to treat different types of anemia. It is taken as the sulfate hydrate salt by mouth. Mitapivat is a pyruvate kinase activator.

The most common side effects include decreases in estrone and estradiol (types of the estrogen hormone) in men, increased urate (a type of salt in the body), back pain, and joint stiffness.

Excerpted from Wikipedia’s “mitapivat” article, available under the CC BY-SA 4.0 licence.

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