Structure via PubChem · Public domain (PubChem)
mitomycin
Sign in to saveAlso known as NSC-26980, MMC, 7-amino-9alpha-methoxymitosane, mitomycin C
chemical compound
In the Vinony graph
Vinony's link graph records 334 inbound references to mitomycin, and connects out to topical medication, antineoplastic and tiazofurin.
It sits within the topics Antineoplastic drugs, Aziridines and Cancer treatments.
Vinony links it to 17 Wikipedia language editions.
Chemical data
- Formula
- C15H18N4O5
- Molecular weight
- 334.33 g/mol
- IUPAC name
- [(4S,6S,7R,8S)-11-amino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate
- SMILES
- CC1=C(C(=O)C2=C(C1=O)N3C[C@H]4[C@@H]([C@@]3([C@@H]2COC(=O)N)OC)N4)N
- InChIKey
- NWIBSHFKIJFRCO-WUDYKRTCSA-N
- XLogP
- -0.4
- Polar surface area
- 147 Ų
- H-bond donors
- 3
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1981
- Admin. routes
- parenteral, topical
- Indications
- neoplasm, Myopia, pterygium, sclerosing cholangitis
via ChEMBL · EBI
Research
24,627 papers- Mitomycin C.Cancer chemotherapy and biological response modifiers · 1990
- Mitomycin C.Cancer chemotherapy and biological response modifiers · 1992
- Mitomycin C.Cancer chemotherapy and biological response modifiers · 1988
- Mitomycin-C in breast cancer.Seminars in oncology · 1985
- Mitomycin C.Cancer chemotherapy and biological response modifiers · 1987
via PubMed
Wikidata facts
- Mass
- 334.12772
- Has use
- medication
Show 8 more facts
- chemical formula
- C₁₅H₁₈N₄O₅
- medical condition treated
- bladder cancer
- subject has role
- carcinogen
- isomeric SMILES
- CC1=C(C(=O)C2=C(C1=O)N3C[C@H]4[C@@H]([C@@]3([C@@H]2COC(=O)N)OC)N4)N
- canonical SMILES
- CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N)OC)N4)N
- different from
- mitomycins
- significant drug interaction
- vinblastine
- legal status (medicine)
- boxed warning
Sources (6)
via Wikidata · CC0
Connections
topical medication
Entity
antineoplastic
Entity
tiazofurin
Entity
liver
Entity
deoxyribonucleic acid
Entity
International Standard Book Number
Entity
eukaryote
Entity
prokaryotes
Entity
public domain
Entity
breast cancer
Entity
digital object identifier
Entity
urinary bladder
Entity
chemical formula
Entity
melting point
Entity
bone marrow
Entity
chemotherapy
Entity
molar mass
Entity
meiosis
Entity
PubMed
Entity
DNA replication
Entity