mixed connective tissue disease

Also known as Rupus, Connective tissue disease overlap syndrome (disorder), mixed collagen vascular disease (disorder), mixed collagen vascular disease, Connective tissue disease overlap syndrome, Sharp syndrome, MCTD

collagen disease that is considered an overlap of three diseases, systemic lupus erythematosus, scleroderma, and polymyositis with very high titers of circulating antinuclear antibody to a ribonucleoprotein antigen