dermatomyositis

Also known as dermatopolymyositis, Dermatopolymyositis, unspecified, Polymyositis with skin involvement, Amyopathic dermatomyositis

Dermatomyositis (DM) is a long-term inflammatory autoimmune disorder which affects the skin and the muscles. Its symptoms are generally a skin rash and worsening muscle weakness over time. These may occur suddenly or develop over months. Other symptoms may include weight loss, fever, lung inflammation, or light sensitivity. Complications may include calcium deposits in muscles or skin.

Key facts

Medical condition (new).caption: Discrete red areas overlying the knuckles in a person with juvenile dermatomyositis. These are known as Gottron's papules.
Medical condition (new).field: Rheumatology
Medical condition (new).symptoms: Rash, muscle weakness, weight loss, fever
Medical condition (new).complications: Calcinosis, dysphagia, interstitial lung disease, heart disease (rarely), joint pain, other autoimmune conditions
Medical condition (new).onset: 40s to 50s
Medical condition (new).duration: Long term
Medical condition (new).causes: Autoimmune (Type III hypersensitivity)
Medical condition (new).risks: Other autoimmune conditions, ovarian cancer, breast cancer, lung cancer, other cancers
Medical condition (new).diagnosis: Based on symptoms, blood tests, electromyography, muscle biopsies
Medical condition (new).differential: Polymyositis, inclusion body myositis, scleroderma
Medical condition (new).treatment: Medication, physical therapy, exercise, heat therapy, orthotics, assistive devices, rest
Medical condition (new).medication: Corticosteroids, methotrexate, azathioprine
Medical condition (new).frequency: ~ 1 per 100,000 people per year
Medical condition (new).name: Dermatomyositis
Medical condition (new).image: Dermatomyositis.jpg

via Wikipedia infobox

Research

14,551 papers

Dermatomyositis: Clinical features and pathogenesis.Journal of the American Academy of Dermatology · 2020
Dermatomyositis: Diagnosis and treatment.Journal of the American Academy of Dermatology · 2020
Juvenile Dermatomyositis-Clinical Phenotypes.Current rheumatology reports · 2019
Polymyositis and dermatomyositis (first of two parts).The New England journal of medicine · 1975
Dermatomyositis.Disease-a-month : DM · 1987

via PubMed

Wikidata facts

Image: XRaydermatomyositis.jpg

Show 6 more facts

Commons category: Dermatomyositis
NCI Thesaurus ID: C26744
exact match: identifiers.org/doid/DOID:10223
ICD-9-CM: 710.3
external data available at URL: www.nanbyou.or.jp/entry/4079
prevalence: 0.0001022

Sources (7)

via Wikidata · CC0

~15 min read

Article

17 sections

Contents

Signs and symptoms
Skin
Muscles
Respiratory
Cardiac
Other
Causes
Diagnosis
Classification
Treatment
Prognosis
Epidemiology
History
People who were affected with dermatomyositis
Research
References
External links

Dermatomyositis is an autoimmune disorder featuring both humoral and T-cell autoimmune processes. Dermatomyositis may develop as a paraneoplastic syndrome associated with several forms of malignancy. It is known to be associated with several viruses, especially coxsackievirus, but no definitive causal link has been found. Dermatomyositis is considered a type of inflammatory myopathy. Diagnosis is typically based on some combination of symptoms, blood tests, electromyography, and muscle biopsies. Eighty percent of adults and sixty percent of children with juvenile dermatomyositis have a myositis-specific antibody (MSA).