MTARC2

Also known as MOSC2, mitochondrial amidoxime reducing component 2, MARC2

MOSC domain-containing protein 2, mitochondrial is a protein that in humans is encoded by the MOSC2 gene.

In the Vinony graph

Within Vinony's link graph, MTARC2 is referenced by 1 other article, and connects out to PubMed, human chromosome 1 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 1.

Its subject is documented across 7 Wikipedia language editions.

Gene data

MTARC2

Name: mitochondrial amidoxime reducing component 2
Type: protein-coding
Position: 220,747,877–220,784,824 (+)
Aliases: MARC2, MOSC2
Ensembl: ENSG00000117791
RefSeq RNA: NM_001317338.2, NM_001331042.2, NM_017898.5, XM_011509684.2, XM_047423617.1
RefSeq protein: NP_001304267.1, NP_001317971.1, NP_060368.2, XP_011507986.1, XP_047279573.1

The protein encoded by this gene is an enzyme found in the outer mitochondrial membrane that reduces N-hydroxylated substrates. The encoded protein uses molybdenum as a cofactor and cytochrome b5 type B and NADH cytochrome b5 reductase as accessory proteins. One type of substrate used is N-hydroxylated nucleotide base analogues, which can be toxic to a cell. Other substrates include N(omega)-hydroxy-L-arginine (NOHA) and amidoxime prodrugs, which are activated by the encoded enzyme. Multiple transcript variants encoding the different isoforms have been found for this gene. [provided by RefSeq, Sep 2016].