neuroblastoma
Neuroblastoma (NB) is a type of cancer that forms in certain types of nerve tissue. It most frequently starts from one of the adrenal glands but can also develop in the neck, chest, abdomen, or spine. Symptoms may include bone pain, a mass in the abdomen, neck, or chest, or painless bluish lumps under the skin.
Key facts
- Medical condition (new).name
- Neuroblastoma
- Medical condition (new).image
- Neuroblastoma rosettes.jpg
- Medical condition (new).caption
- Microscopic view of a typical neuroblastoma with rosette formation
- Medical condition (new).image_size
- 300px
- Medical condition (new).field
- Neuro-oncology
- Medical condition (new).symptoms
- Bone pain, lumps
- Medical condition (new).onset
- Under 5 years old
- Medical condition (new).causes
- Genetic mutation
- Medical condition (new).diagnosis
- Tissue biopsy
- Medical condition (new).treatment
- Observation, surgery, radiation, chemotherapy, stem cell transplantation
- Medical condition (new).prognosis
- US five-year survival ~95% (< 1 year old), 68% (1–14 years old)
Article
21 sectionsContents
- Signs and symptoms
- Cause
- Diagnosis
- Biochemistry
- Imaging
- Histology
- Staging
- Screening
- Treatment
- Prognosis
- Cytogenetic profiles
- Epidemiology
- History
- Scientific research
- Preclinical models
- Treatments
- Refractory and relapsed neuroblastoma
- Electronic health records' data
- Organisations
- References
- External links
Neuroblastoma (NB) is a type of cancer that forms in certain types of nerve tissue. It most frequently starts from one of the adrenal glands but can also develop in the neck, chest, abdomen, or spine. Symptoms may include bone pain, a mass in the abdomen, neck, or chest, or painless bluish lumps under the skin.
Typically, neuroblastoma occurs due to a genetic mutation occurring in the first trimester of pregnancy. Rarely, it may be due to a mutation inherited. Environmental factors have not been found to be involved. Diagnosis is based on a tissue biopsy. Occasionally, it may be found in a baby by ultrasound during pregnancy. At diagnosis, the cancer has usually already spread. The cancer is divided into low-, intermediate-, and high-risk groups based on a child's age, cancer stage, and what the cancer looks like.