NFKBIB
Sign in to saveAlso known as IKBB, TRIP9, NFKB inhibitor beta
NF-kappa-B inhibitor beta is a protein that in humans is encoded by the NFKBIB gene.
In the Vinony graph
Within Vinony's link graph, NFKBIB is referenced by 7 other articles, and connects out to PubMed, human chromosome 19 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 19.
Its subject is documented across 6 Wikipedia language editions.
Gene data
NFKBIB- Name
- NFKB inhibitor beta
- Type
- protein-coding
- Position
- 38,899,700–38,908,893 (+)
- Aliases
- IKBB, TRIP9
- Ensembl
- ENSG00000282905
- RefSeq RNA
- NM_001001716.1, NM_001243116.2, NM_001369699.1, NM_001369700.1, NM_002503.5
- RefSeq protein
- NP_001230045.1, NP_001356628.1, NP_001356629.1, NP_002494.2, XP_006723289.2
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
NFKB inhibitor beta
- Symbol
- NFKBIB
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:38,899,700-38,908,893
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 37631
- exact match
- identifiers.org/ncbigene/4793
- found in taxon
- Homo sapiens
- chromosome
- human chromosome 19
- genomic start
- 39390340
- genomic end
- 39399533
- cytogenetic location
- 19q13.2
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
NF-kappa-B inhibitor beta is a protein that in humans is encoded by the NFKBIB gene.
== Function ==
Excerpted from Wikipedia’s “NFKBIB” article, available under the CC BY-SA 4.0 licence.