NFKBIB
Sign in to saveAlso known as IKBB, TRIP9, NFKB inhibitor beta
NF-kappa-B inhibitor beta is a protein that in humans is encoded by the NFKBIB gene.
Gene data
NFKBIB- Name
- NFKB inhibitor beta
- Type
- protein-coding
- Position
- 38,899,700–38,908,893 (+)
- Aliases
- IKBB, TRIP9
- Ensembl
- ENSG00000282905
- RefSeq RNA
- NM_001001716.1, NM_001243116.2, NM_001369699.1, NM_001369700.1, NM_002503.5
- RefSeq protein
- NP_001230045.1, NP_001356628.1, NP_001356629.1, NP_002494.2, XP_006723289.2
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 37631
- exact match
- identifiers.org/ncbigene/4793
- genomic start
- 39390340
- genomic end
- 39399533
- cytogenetic location
- 19q13.2
Sources (3)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- Interactions
- References
- Further reading
NF-kappa-B inhibitor beta is a protein that in humans is encoded by the NFKBIB gene.
== Function ==