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نیتمازپام

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EntityQ62014635· pop 5· linked from 409 articles

نیتمازپام

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Nitemazepam (or 3-hydroxynimetazepam) is a benzodiazepine derivative which was first synthesised in the 1970s but was never marketed. It is the 7-nitro instead of 7-chloro analogue of temazepam, and also the 3-hydroxy derivative of nimetazepam, and an active metabolite. It has in more recent years been sold as a designer drug, first being definitively identified in Europe in 2017. It is metabolized to 7-aminonitemazepam, nimetazepam, 3-hydroxynitemazepam, temazepam, and nimetazepam glucuronide.

Chemical data

Formula
C16H13N3O4
Molecular weight
311.29 g/mol
IUPAC name
3-hydroxy-1-methyl-7-nitro-5-phenyl-3H-1,4-benzodiazepin-2-one
SMILES
CN1C2=C(C=C(C=C2)[N+](=O)[O-])C(=NC(C1=O)O)C3=CC=CC=C3
InChIKey
QRWVNMAJJIQCEG-UHFFFAOYSA-N
XLogP
1.4
Polar surface area
98.7 Ų
H-bond donors
1
H-bond acceptors
5
Formal charge
0

via PubChem

Wikidata facts

Show 2 more facts
different from
nitrazepam
subject has role
benzodiazepine drug
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