Structure via PubChem · Public domain (PubChem)
Nitemazepam
Sign in to saveNitemazepam (or 3-hydroxynimetazepam) is a benzodiazepine derivative which was first synthesised in the 1970s but was never marketed. It is the 7-nitro instead of 7-chloro analogue of temazepam, and also the 3-hydroxy derivative of nimetazepam, and an active metabolite. It has in more recent years been sold as a designer drug, first being definitively identified in Europe in 2017. It is metabolized to 7-aminonitemazepam, nimetazepam, 3-hydroxynitemazepam, temazepam, and nimetazepam glucuronide.
Chemical data
- Formula
- C16H13N3O4
- Molecular weight
- 311.29 g/mol
- IUPAC name
- 3-hydroxy-1-methyl-7-nitro-5-phenyl-3H-1,4-benzodiazepin-2-one
- SMILES
- CN1C2=C(C=C(C=C2)[N+](=O)[O-])C(=NC(C1=O)O)C3=CC=CC=C3
- InChIKey
- QRWVNMAJJIQCEG-UHFFFAOYSA-N
- XLogP
- 1.4
- Polar surface area
- 98.7 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- benzodiazepine drug
Show 2 more facts
- different from
- nitrazepam
- subject has role
- benzodiazepine drug
Sources (1)
via Wikidata · CC0
Article · Italiano
Il nitemazepam è uno psicofarmaco appartenente alla categoria delle benzodiazepine sintetizzato per la prima volta negli anni '70 ma non è mai stato commercializzato. Viene identificato per la prima volta in Europa nel 2017.
Abstract from DBpedia / Wikipedia · CC BY-SA