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nitemazepam
Sign in to saveNitemazepam (or 3-hydroxynimetazepam) is a benzodiazepine derivative which was first synthesised in the 1970s but was never marketed. It is the 7-nitro instead of 7-chloro analogue of temazepam, and also the 3-hydroxy derivative of nimetazepam, and an active metabolite. It has in more recent years been sold as a designer drug, first being definitively identified in Europe in 2017. It is metabolized to 7-aminonitemazepam, nimetazepam, 3-hydroxynitemazepam, temazepam, and nimetazepam glucuronide.
In the Vinony graph
Within Vinony's link graph, nitemazepam is referenced by 409 other articles, and connects out to benzodiazepine drug, allopregnanolone and isovaleric acid.
It is catalogued under topics including Chemical pages without DrugBank identifier, Designer drugs and Drugs missing an ATC code.
Its subject is documented across 5 Wikipedia language editions.
Chemical data
- Formula
- C16H13N3O4
- Molecular weight
- 311.29 g/mol
- IUPAC name
- 3-hydroxy-1-methyl-7-nitro-5-phenyl-3H-1,4-benzodiazepin-2-one
- SMILES
- CN1C2=C(C=C(C=C2)[N+](=O)[O-])C(=NC(C1=O)O)C3=CC=CC=C3
- InChIKey
- QRWVNMAJJIQCEG-UHFFFAOYSA-N
- XLogP
- 1.4
- Polar surface area
- 98.7 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- benzodiazepine drug
Show 2 more facts
- different from
- nitrazepam
- subject has role
- benzodiazepine drug
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Nitemazepam (or 3-hydroxynimetazepam) is a benzodiazepine derivative which was first synthesised in the 1970s but was never marketed. It is the 7-nitro instead of 7-chloro analogue of temazepam, and also the 3-hydroxy derivative of nimetazepam, and an active metabolite. It has in more recent years been sold as a designer drug, first being definitively identified in Europe in 2017. It is metabolized to 7-aminonitemazepam, nimetazepam, 3-hydroxynitemazepam, temazepam, and nimetazepam glucuronide.
==References==
Excerpted from Wikipedia’s “nitemazepam” article, available under the CC BY-SA 4.0 licence.