NS-2359
Sign in to saveAlso known as GSK-372475
NS-2359 (GSK-372475) is a serotonin-norepinephrine-dopamine reuptake inhibitor. It was under development by GlaxoSmithKline (GSK) as an antidepressant, but was discontinued in 2009 when phase II clinical trials showed the drug was not effective and not well tolerated. The results did not support further effort by the company. NS-2359 was also in clinical trials for the treatment of ADHD, phase II having been completed in 2007. A phase I clinical trial exploring the effect of NS-2359 on cocaine-dependent individuals was completed in 2002.
Wikidata facts
- Has part
- chlorine
- Mass
- 299.08437
Show 4 more facts
- chemical formula
- C₁₅H₁₉Cl₂NO
- canonical SMILES
- COCC1C2CCC(N2)CC1C3=CC(=C(C=C3)Cl)Cl
- isomeric SMILES
- COC[C@H]1[C@H]2CC[C@H](N2)C[C@@H]1C3=CC(=C(C=C3)Cl)Cl
- Commons category
- NS-2359
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Encyclopedic overview
2 sectionsContents
- See also
- References
NS-2359 (GSK-372475) is a serotonin-norepinephrine-dopamine reuptake inhibitor. It was under development by GlaxoSmithKline (GSK) as an antidepressant, but was discontinued in 2009 when phase II clinical trials showed the drug was not effective and not well tolerated. The results did not support further effort by the company. NS-2359 was also in clinical trials for the treatment of ADHD, phase II having been completed in 2007. A phase I clinical trial exploring the effect of NS-2359 on cocaine-dependent individuals was completed in 2002.
== See also == Tesofensine
Excerpted from Wikipedia’s “NS-2359” article, available under the CC BY-SA 4.0 licence.