NTSR2

Name

neurotensin receptor 2

Type

protein-coding

Position

11,658,161–11,670,346 (−)

Aliases

NTR2

Ensembl

ENSG00000169006

RefSeq RNA

NM_012344.4, XM_005246156.4, XM_006711876.5, XM_006711877.4, XM_017003738.2

RefSeq protein

NP_036476.2, XP_005246213.1, XP_006711939.1, XP_006711940.1, XP_016859227.1

The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

neurotensin receptor 2

Symbol

NTSR2

Biotype

Protein coding

Organism

Homo sapiens

Location

2:11,658,161-11,670,346

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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