odevixibat
Sign in to saveAlso known as Bylvay, (2S)-2-[[(2R)-2-[[2-[(3,3-dibutyl-7-methylsulfanyl-1,1-dioxo-5-phenyl-2,4-dihydro-1lambda6,2,5-benzothiadiazepin-8-yl)oxy]acetyl]amino]-2-(4-hydroxyphenyl)acetyl]amino]butanoic acid
Odevixibat, sold under the brand name Bylvay among others, is a medication for the treatment of progressive familial intrahepatic cholestasis. It is taken by mouth. Odevixibat is a reversible, potent, selective inhibitor of the ileal bile acid transporter (IBAT). It was developed by Albireo Pharma.
Wikidata facts
- Mass
- 740.2913564959999
Show 4 more facts
- canonical SMILES
- CCCCC1(CN(C2=CC(=C(C=C2S(=O)(=O)N1)OCC(=O)NC(C3=CC=C(C=C3)O)C(=O)NC(CC)C(=O)O)SC)C4=CC=CC=C4)CCCC
- isomeric SMILES
- CCCCC1(CN(C2=CC(=C(C=C2S(=O)(=O)N1)OCC(=O)N[C@H](C3=CC=C(C=C3)O)C(=O)N[C@@H](CC)C(=O)O)SC)C4=CC=CC=C4)CCCC
- chemical formula
- C₃₇H₄₈N₄O₈S₂
- Commons category
- Odevixibat
Sources (1)
via Wikidata · CC0
~8 min read
Article
12 sectionsContents
- Medical uses
- Mechanism of action
- Pharmacokinetics
- Contraindications
- Adverse effects
- Pregnancy and lactation
- History
- Society and culture
- Legal status
- Research
- References
- External links
{{Infobox drug | image = Odevixibat.svg | image_class = skin-invert-image | width = | alt = | caption =
| pronounce = | tradename = Bylvay | Drugs.com = | MedlinePlus = a621049 | DailyMedID = Odevixibat | pregnancy_AU = | pregnancy_AU_comment = | pregnancy_category= | routes_of_administration = By mouth | class = | ATC_prefix = A05 | ATC_suffix = AX05 | ATC_supplemental =