OTOG
Sign in to saveAlso known as DFNB18B, MLEMP, OTGN, otogelin
Otogelin is a protein that in humans is encoded by the OTOG gene.
Gene data
OTOG- Name
- otogelin
- Type
- protein-coding
- Aliases
- DFNB18B, MLEMP, OTGN
The protein encoded by this gene is a component of the acellular membranes of the inner ear. Disruption of the orthologous mouse gene shows that it plays a role in auditory and vestibular functions. It is involved in fibrillar network organization, the anchoring of otoconial membranes and cupulae to the neuroepithelia, and likely in sound stimulation resistance. Mutations in this gene cause autosomal recessive nonsyndromic deafness, type 18B. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014].
via MyGene.info
Gene · Ensembl
otogelin
- Symbol
- OTOG
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:17,547,259-17,647,150
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 8421
- exact match
- identifiers.org/ncbigene/340990
- genomic end
- 17668697
- genomic start
- 17547259
- cytogenetic location
- 11p15.1
Sources (6)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- Deafness
- References
- Further reading
Otogelin is a protein that in humans is encoded by the OTOG gene.
==Function==