OTOR

Also known as FDP, MIAL1, otoraplin

Otoraplin is a protein that in humans is encoded by the OTOR gene.

In the Vinony graph

Within Vinony's link graph, OTOR is referenced by 3 other articles, and connects out to PubMed, human chromosome 20 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 20.

Its subject is documented across 6 Wikipedia language editions.

Gene data

OTOR

Name: otoraplin
Type: protein-coding
Position: 16,748,358–16,770,062 (+)
Aliases: FDP, MIAL1
Ensembl: ENSG00000125879
RefSeq RNA: NM_020157.4, XM_017027959.3, XM_054323723.1
RefSeq protein: NP_064542.1, XP_016883448.1, XP_054179698.1

This gene encodes a member of the melanoma-inhibiting activity gene family. The encoded protein is secreted via the Golgi apparatus and may function in cartilage development and maintenance. A frequent polymorphism in the translation start codon of this gene can abolish translation and may be associated with forms of deafness. [provided by RefSeq, Jul 2013].

Gene Ontology

Biological process

cartilage condensation sensory perception of sound

Molecular function

protein binding

Cellular component

extracellular region

via MyGene.info

Gene · Ensembl

otoraplin

Symbol: OTOR
Biotype: Protein coding
Organism: Homo sapiens
Location: 20:16,748,358-16,770,062
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 10600
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/56914
genomic end: 16750707
genomic start: 16729003
chromosome: human chromosome 20
cytogenetic location: 20p12.1
expressed in: gallbladder

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections

Contents

References
Further reading

Otoraplin is a protein that in humans is encoded by the OTOR gene.

The protein encoded by this gene is secreted via the Golgi apparatus and may function in cartilage development and maintenance. A frequent polymorphism in the translation start codon of this gene can abolish translation and may be associated with forms of deafness. This gene is a member of the melanoma-inhibiting activity gene family. In addition, alternate polyA sites exist for this gene.

Excerpted from Wikipedia’s “OTOR” article, available under the CC BY-SA 4.0 licence.