Structure via PubChem · Public domain (PubChem)
oxyphenbutazone
Sign in to saveAlso known as Tandearil, Oxiphenbutazone, Oxifenbutazona, Oxyphenbutazonum, 1-Phenyl-2-(p-hydroxyphenyl)-3,5-dioxo-4-n-butylpyrazolidine, p-Hydroxyphenylbutazone, Oxi-fenibutol, 3,5-Dioxo-1-phenyl-2-(p-hydroxyphenyl)-4-N-butylpyrazolidene
Oxyphenbutazone is a nonsteroidal anti-inflammatory drug (NSAID). It is a metabolite of phenylbutazone.
Chemical data
- Formula
- C19H20N2O3
- Molecular weight
- 324.4 g/mol
- IUPAC name
- 4-butyl-1-(4-hydroxyphenyl)-2-phenylpyrazolidine-3,5-dione
- SMILES
- CCCCC1C(=O)N(N(C1=O)C2=CC=C(C=C2)O)C3=CC=CC=C3
- InChIKey
- HFHZKZSRXITVMK-UHFFFAOYSA-N
- XLogP
- 2.7
- Polar surface area
- 60.9 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
Withdrawn- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1960
- Admin. routes
- oral
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 324.147393
- Has use
- medication
Show 3 more facts
- chemical formula
- C₁₉H₂₀N₂O₃
- canonical SMILES
- CCCCC1C(=O)N(N(C1=O)C2=CC=C(C=C2)O)C3=CC=CC=C3
- World Health Organisation international non-proprietary name
- oxyphenbutazone
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Oxyphenbutazone is a nonsteroidal anti-inflammatory drug (NSAID). It is a metabolite of phenylbutazone.
It was withdrawn from markets worldwide in the mid-1980s due to bone marrow suppression and the risk of Stevens–Johnson syndrome.
Excerpted from Wikipedia’s “oxyphenbutazone” article, available under the CC BY-SA 4.0 licence.
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