پنتاگاسترین

Key facts

Drug.Watchedfields

changed

Drug.verifiedrevid

464198043

Drug.IUPAC_name

N-(tert-butoxycarbonyl)-β-alanyl-L-tryptophyl-L-methionyl-L-α-aspartyl-L-phenylalaninamide

Drug.image

Pentagastrin.svg

Drug.image_class

skin-invert-image

Drug.elimination_half life

10 minutes or less

Drug.CAS_number

5534-95-2

Drug.ATC_prefix

V04

Drug.ATC_suffix

CG04

Drug.PubChem

9853654

Drug.IUPHAR_ligand

870

Drug.DrugBank

DB00183

Drug.ChemSpiderID

8029364

Drug.UNII

EF0NX91490

Drug.KEGG

D01631

Drug.ChEMBL

1328

Drug.C

37

Drug.H

49

via Wikipedia infobox

Chemical data

Formula

C37H49N7O9S

Molecular weight

767.9 g/mol

IUPAC name

(3S)-4-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2S)-2-[[(2S)-3-(1H-indol-3-yl)-2-[3-[(2-methylpropan-2-yl)oxycarbonylamino]propanoylamino]propanoyl]amino]-4-methylsulfanylbutanoyl]amino]-4-oxobutanoic acid

SMILES

CC(C)(C)OC(=O)NCCC(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N

InChIKey

NEYNJQRKHLUJRU-DZUOILHNSA-N

XLogP

1.5

Polar surface area

276 Ų

H-bond donors

8

H-bond acceptors

10

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Approved

Molecule type

Small molecule

First approval

1974

Admin. routes

parenteral

via ChEMBL · EBI

• Pentagastrin.The Medical letter on drugs and therapeutics · 1975
• Pentagastrin-induced thrombocytopenia.Lancet (London, England) · 1985
• Pentagastrin test for anxiety--psychophysiology and personality.Psychopharmacology · 2003
• Pentagastrin has panic-inducing properties in obsessive compulsive disorder.Psychopharmacology · 1996
• [Trophic effect of gastroenteric hormones pentagastrin and glucagon on the mucosa of the small intestine].Polski tygodnik lekarski (Warsaw, Poland : 1960) · 1989

via PubMed

Wikidata facts

Has part

carbon

Mass

767.331247

Has use

medication

via Wikidata · CC0