betazole
Sign in to saveAlso known as ametazole, Histalog®, 3-(beta-aminoethyl)pyrazole, 3-(2-aminoethyl)pyrazole, 2-(3-pyrazolyl)ethylamine, 1H-pyrazole-3-ethanamine, 2-(1H-pyrazol-5-yl)ethanamine, 2-(1H-pyrazol-5-yl)ethan-1-amine
Betazole (also known as ametazole) is a histamine H2 receptor agonist. Betazole hydrochloride is known as gastramine and histalog.
Research
282 papers- Betazole-induced GIP secretion is not mediated by gastric HCl.Metabolism: clinical and experimental · 1982
- BETAZOLE Hydrochloride.Journal of the American Medical Association · 1956
- Biocatalytic access to betazole using a one-pot multienzymatic system in continuous flow.Green chemistry : an international journal and green chemistry resource : GC · 2021
- Effects of betazole hydrochloride and cyclic AMP on the pepsinogen secretion by rabbit gastric mucosa in organ culture.Digestion · 1982
- Effects of cyclic nucleotides, betazole hydrochloride and acetylcholine on pepsinogen secretion from isolated rabbit gastric mucosa.Gastroenterologia Japonica · 1986
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 111.08
- Has use
- medication
Show 4 more facts
- Commons category
- Betazole
- chemical formula
- C₅H₉N₃
- canonical SMILES
- C1=C(NN=C1)CCN
- World Health Organisation international non-proprietary name
- betazole
Sources (2)
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Encyclopedic overview
1 sectionsContents
- References
Betazole (also known as ametazole) is a histamine H2 receptor agonist. Betazole hydrochloride is known as gastramine and histalog.
It has been used as a gastric stimulant to test for maximal production of gastric secretion activity. The test can be used in diagnosis of diseases such as Zollinger-Ellison syndrome where there is excess acid production, in this case driven by over production of gastrin. The volume of acid secretion is measured following administration of betazole, diagnosis being secretion greater than 60% of the maximal acid secretion following betazole stimulation. This procedure can lead to complications and should be avoided in subjects with coronary artery disease. It is also used in diagnosis of gastritis in association with a test for secretin activity.
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