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ProteinQ700006· pop 7· linked from 448 articles

Phospholipase B1

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Also known as phospholipase A2, phospholipase B1, membrane-associated, lysophospholipase, PLB1, phospholipase B/lipase, PLB/LIP

mammalian protein found in Homo sapiens

Protein · UniProt

Phospholipase B1, membrane-associated

Gene
PLB1
Organism
Homo sapiens (Human)
Length
1,458 aa
Molecular mass
163,081 Da
Evidence
1: Evidence at protein level

Calcium-independent membrane-associated phospholipase that catalyzes complete diacylation of phospholipids by hydrolyzing both sn-1 and sn-2 fatty acyl chains attached to the glycerol backbone (phospholipase B activity) (By similarity). Has dual phospholipase and lysophospholipase activities toward diacylphospholipids. Preferentially cleaves sn-2 ester bonds over sn-1 bonds. Acts as a lipase toward glycerolipid substrates (By similarity). Hydrolyzes fatty acyl chains of diacylglycerols with preference for the sn-2 position and of triacylglycerols with not positional selectivity (By similari…

Alternative splicingCell membraneGlycoproteinHydrolaseLipid metabolismMembranePhospholipid metabolismProteomics identification
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Swiss-Prot (reviewed) · via UniProt

Wikidata facts

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