EntityQ417489· pop 21· linked from 262 articles

pimecrolimus

Pimecrolimus is an immunosuppressant drug of the calcineurin inhibitor class used in the treatment of atopic dermatitis (eczema).

Key facts

Drug.IUPAC_name: (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-3-{(E)-2-[(1R,3R,4S)-4-chloro-3-methoxycyclohexyl]-1-methylvinyl}-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosin-1,7,20,21(4H,23H)-tetrone
Drug.image: Pimecrolimus.svg
Drug.image_class: skin-invert-image
Drug.width: 200
Drug.image2: Pimecrolimus ball-and-stick.png
Drug.image_class2: bg-transparent
Drug.tradename: Elidel
Drug.pregnancy_AU: B3
Drug.pregnancy_US: C
Drug.legal_US: Rx-only
Drug.routes_of_administration: topical
Drug.class: immunosuppressant
Drug.bioavailability: low systemic absorption
Drug.protein_bound: 74%–87%
Drug.metabolism: Hepatic CYP3A
Drug.CAS_number: 137071-32-0
Drug.ATC_prefix: D11
Drug.ATC_suffix: AH02

via Wikipedia infobox

Article

7 sections

Contents

Medical uses
Atopic dermatitis
Side effects
Pharmacology
Development and production
References
External links

{{Infobox drug | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 464206673 | IUPAC_name = (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-3-{(E)-2-[(1R,3R,4S)-4-chloro-3-methoxycyclohexyl]-1-methylvinyl}-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosin-1,7,20,21(4H,23H)-tetrone | image = Pimecrolimus.svg | image_class = skin-invert-image | width = 200 | image2 = Pimecrolimus ball-and-stick.png | image_class2 = bg-transparent