Structure via PubChem · Public domain (PubChem)
PK-11195
Sign in to saveAlso known as 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide, RP 52028, PK 11195, PK11195
chemical compound
Chemical data
- Formula
- C21H21ClN2O
- Molecular weight
- 352.9 g/mol
- IUPAC name
- N-butan-2-yl-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide
- SMILES
- CCC(C)N(C)C(=O)C1=CC2=CC=CC=C2C(=N1)C3=CC=CC=C3Cl
- InChIKey
- RAVIZVQZGXBOQO-UHFFFAOYSA-N
- XLogP
- 5.5
- Polar surface area
- 33.2 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
1,190 papers- Global brain inflammation in stroke.The Lancet. Neurology · 2019
- The Protective Effect of PK-11195 on Cognitive Impairment in Rats Survived of Polymicrobial Sepsis.Molecular neurobiology · 2021
- PK 11195 reduces the brain availability of lindane in rats and the convulsions induced by this neurotoxic agent.Life sciences · 1995
- The pharmacodynamics of PK 11195 in diazepam-dependent male and female rats.Pharmacology, biochemistry, and behavior · 2000
- Membrane-Mediated Ligand Unbinding of the PK-11195 Ligand from TSPO.Biophysical journal · 2021
via PubMed
Wikidata facts
- Mass
- 352.134241
Show 4 more facts
- chemical formula
- C₂₁H₂₁ClN₂O
- canonical SMILES
- CCC(C)N(C)C(=O)C1=CC2=CC=CC=C2C(=N1)C3=CC=CC=C3Cl
- subject has role
- antineoplastic
- Commons category
- PK-11195
Sources (2)
via Wikidata · CC0