PSRC1
Sign in to saveAlso known as DDA3, FP3214, proline and serine rich coiled-coil 1
Proline/serine-rich coiled-coil protein 1 is a protein that in humans is encoded by the PSRC1 gene.
In the Vinony graph
Vinony's link graph records 2 inbound references to PSRC1, and connects out to PubMed, Ensembl genome database project and protein.
It is catalogued under the topic Genes on human chromosome 1.
Vinony links it to 6 Wikipedia language editions.
Gene data
PSRC1- Name
- proline and serine rich coiled-coil 1
- Type
- protein-coding
- Position
- 109,279,053–109,284,107 (−)
- Aliases
- DDA3, FP3214
- Ensembl
- ENSG00000134222
- RefSeq RNA
- NM_001005290.4, NM_001032290.1, NM_001032291.3, NM_001350237.2, NM_001350238.2
- RefSeq protein
- NP_001005290.1, NP_001027462.1, NP_001337166.1, NP_001337167.1, NP_001337168.1
This gene encodes a proline-rich protein that is a target for regulation by the tumor suppressor protein p53. The encoded protein plays an important role in mitosis by recruiting and regulating microtubule depolymerases that destabalize microtubules. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Apr 2014].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
proline and serine rich coiled-coil 1
- Symbol
- PSRC1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:109,279,053-109,284,107
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 49603
- genetic association
- coronary artery disease
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/84722
- genomic end
- 109825808
- genomic start
- 109822178
- chromosome
- human chromosome 1
- cytogenetic location
- 1p13.3
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Proline/serine-rich coiled-coil protein 1 is a protein that in humans is encoded by the PSRC1 gene.
This gene encodes a proline-rich protein. Studies of the related mouse gene suggest that this gene is regulated by p53 and may participate in p53-mediated growth suppression. Alternatively spliced transcript variants encoding different isoforms have been described.
Excerpted from Wikipedia’s “PSRC1” article, available under the CC BY-SA 4.0 licence.