RB1CC1
Sign in to saveAlso known as ATG17, CC1, FIP200, PPP1R131, RB1 inducible coiled-coil 1
RB1-inducible coiled-coil protein 1 is a protein that in humans is encoded by the RB1CC1 gene.
Gene data
RB1CC1- Name
- RB1 inducible coiled-coil 1
- Type
- protein-coding
- Position
- 52,622,458–52,745,843 (−)
- Aliases
- ATG17, CC1, FIP200, PPP1R131
- Ensembl
- ENSG00000023287
- RefSeq RNA
- NM_001083617.2, NM_014781.5, XM_011517643.2, XM_011517644.4, XM_011517645.3
- RefSeq protein
- NP_001077086.1, NP_055596.3, XP_011515945.1, XP_011515946.1, XP_011515947.1
The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2009].
Gene Ontology
Biological process
Molecular function
Pathways
Autophagy - animal - Homo sapiens (human)Longevity regulating pathway - Homo sapiens (human)Alzheimer disease - Homo sapiens (human)Amyotrophic lateral sclerosis - Homo sapiens (human)Huntington disease - Homo sapiens (human)Spinocerebellar ataxia - Homo sapiens (human)Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)MacroautophagyAutophagyPI3K-AKT-mTOR signaling pathway and therapeutic opportunities
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 7659
- exact match
- identifiers.org/ncbigene/9821
- genomic end
- 53658403
- genomic start
- 52622458
- cytogenetic location
- 8q11.23
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Interactions
- References
- Further reading
RB1-inducible coiled-coil protein 1 is a protein that in humans is encoded by the RB1CC1 gene.
== Interactions ==
Connections
Q180686
Entity
human chromosome 8
Entity
Ensembl genome database project
Entity
protein
Entity
Wikidata
Entity
gene
Entity
chromosome
Entity
digital object identifier
Entity
bibcode
Entity
human genome
Entity
Q229883
Entity
base pair
Entity
locus
Entity
gene expression
Entity
Online Mendelian Inheritance in Man
Entity
Q22908627
Entity
Entrez
Entity
Q905695
Entity
Gene Ontology
Entity
protein-protein interaction
Entity