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radezolid
Sign in to saveRadezolid (INN, codenamed RX-1741) is a novel oxazolidinone antibiotic being developed by Melinta Therapeutics, Inc. for the treatment of bacterial acne.
Research
40 papers- In vitro activity of radezolid against Enterococcus faecium and compared with linezolid.The Journal of antibiotics · 2020
- Radezolid Is More Effective Than Linezolid Against Planktonic Cells and Inhibits Enterococcus faecalis Biofilm Formation.Frontiers in microbiology · 2020
- Investigation of radezolid interaction with non-canonical chloramphenicol binding site by molecular dynamics simulations.Journal of molecular graphics & modelling · 2021
- Antibacterial and anti-biofilm activity of radezolid against Staphylococcus aureus clinical isolates from China.Frontiers in microbiology · 2023
- Mitoribosome-Targeting Antibiotics Suppress Osteoclastogenesis and Periodontitis-Induced Bone Loss by Blocking Mitochondrial Protein Synthesis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 438.182
Show 4 more facts
- chemical formula
- C₂₂H₂₃FN₆O₃
- canonical SMILES
- CC(=O)NCC1CN(C(=O)O1)C2=CC(=C(C=C2)C3=CC=C(C=C3)CNCC4=NNN=C4)F
- isomeric SMILES
- CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)C3=CC=C(C=C3)CNCC4=NNN=C4)F
- subject has role
- antibiotic
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
{{Drugbox | IUPAC_name = N-{[(5S)-3-(2-fluoro-4′-{[(1H-1,2,3-triazol-5-ylmethyl)amino]methyl}biphenyl-4-yl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide | image = Radezolid.svg | image_class = skin-invert-image | alt = Skeletal formula of radezolid
| tradename = | legal_status = Investigational | routes_of_administration = Intravenous infusion, oral
Excerpted from Wikipedia’s “radezolid” article, available under the CC BY-SA 4.0 licence.