Relaxin

Also known as IPR022421

Relaxin is a protein hormone of about 6000 Da, first described in 1926 by Frederick Hisaw.

In the Vinony graph

Within Vinony's link graph, Relaxin is referenced by 223 other articles, and connects out to human pregnancy, matrix metalloproteinases and RXFP1.

It sits within the topics Genes on human chromosome 19, Genes on human chromosome 9 and Hormones of the ovary.

Its subject is documented across 24 Wikipedia language editions.

Key facts

Protein.Name: Relaxin 3
Protein.image: relaxin.png
Protein.HGNCid: 17135
Protein.Symbol: RLN3
Protein.AltSymbols: ZINS4, RXN3, H3
Protein.EntrezGene: 117579
Protein.OMIM: 606855
Protein.RefSeq: NM_080864
Protein.UniProt: Q8WXF3
Protein.Chromosome: 19
Protein.Arm: p
Protein.Band: 13.3
Protein.LocusSupplementaryData: -q12
Protein.PDB: 6RLX

via Wikipedia infobox

Research

3,955 papers

Relaxin suppresses atrial fibrillation, reverses fibrosis and reduces inflammation in aged hearts.Biochemical pharmacology · 2024
Relaxin.Annual review of physiology · 1984
Understanding relaxin signalling at the cellular level.Molecular and cellular endocrinology · 2019
Relaxin--a review.The Australian & New Zealand journal of obstetrics & gynaecology · 1981
Cardioprotective actions of relaxin.Molecular and cellular endocrinology · 2019

via PubMed

Wikidata facts

Instance of: protein family
Subclass of: peptide hormone
Image: Relaxin.png

Show 1 more fact

Commons category: Relaxin

Sources (4)

via Wikidata · CC0

~9 min read

Encyclopedic overview

16 sections

Contents

Synthesis
Structure
Function in humans
Reproduction
Cardiovascular function
Function in other animals
Reproduction
Cardiovascular function
Receptors
Disorders
Pregnancy
Pharmacological targets
Evolution
See also
References
External links

Relaxin is a protein hormone of about 6000 Da, first described in 1926 by Frederick Hisaw.

The relaxin family peptide hormones belong to the insulin superfamily and consists of seven peptides of high structural but low sequence similarity; relaxin-1 (RLN1), 2 (RLN2) and 3 (RLN3), and the insulin-like (INSL) peptides, INSL3, INSL4, INSL5 and INSL6. The functions of relaxin-3, INSL4, INSL5, and INSL6 remain uncharacterised.

Excerpted from Wikipedia’s “Relaxin” article, available under the CC BY-SA 4.0 licence.