(S)-duloxetine
Duloxetine, sold under the brand name Cymbalta among others, is a medication used to treat major depressive disorder, generalized anxiety disorder, obsessive–compulsive disorder, fibromyalgia, neuropathic pain, central sensitization, and other types of chronic pain. It is taken by mouth.
Key facts
- Drug.Verifiedfields
- changed
- Drug.verifiedrevid
- 460765928
- Drug.image
- Duloxetine.svg
- Drug.image_class
- skin-invert-image
- Drug.image2
- Duloxetine-hydrochloride-from-xtal-3D-bs-17.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Cymbalta, others
- Drug.MedlinePlus
- a604030
- Drug.DailyMedID
- Duloxetine
- Drug.pregnancy_AU
- B3
- Drug.routes_of_administration
- By mouth
- Drug.class
- Serotonin–norepinephrine reuptake inhibitor (SNRI)
Article
26 sectionsContents
- Medical uses
- Painful diabetic peripheral neuropathy
- Major depressive disorder
- Generalized anxiety disorder
- Neuropathic pain
- Fibromyalgia and chronic pain
- Stress urinary incontinence
- Contraindications
- Adverse effects
- Sexual dysfunction
- Increased sweating
- Discontinuation syndrome
- Suicidality
- Postmarketing reports
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- Absorption
- Distribution
- Metabolism
- Elimination
- Research directions
- History
- See also
- Explanatory notes
- References
Duloxetine, sold under the brand name Cymbalta among others, is a medication used to treat major depressive disorder, generalized anxiety disorder, obsessive–compulsive disorder, fibromyalgia, neuropathic pain, central sensitization, and other types of chronic pain. It is taken by mouth.
Duloxetine is a serotonin–norepinephrine reuptake inhibitor (SNRI). The precise mechanism for its antidepressant and anxiolytic effects is not known.
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AntidepressantsChemical articles with multiple CAS registry numbersChemical articles with multiple ChEBIsChemicals using indexlabelsCYP2D6 inhibitorsDrugboxes which contain changes to verified fieldsDrugs developed by Eli Lilly and CompanyDrugs with non-standard legal statusECHA InfoCard ID from WikidataMultiple chemicals in Infobox drugNaphthol ethers