S1PR2
Sign in to saveAlso known as AGR16, EDG-5, EDG5, Gpcr13, H218, LPB2, S1P2, DFNB68
Sphingosine-1-phosphate receptor 2, also known as S1PR2 or S1P2, is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P).
Gene data
S1PR2- Name
- sphingosine-1-phosphate receptor 2
- Type
- protein-coding
- Position
- 10,221,433–10,231,331 (−)
- Aliases
- AGR16, DFNB68, EDG-5, EDG5, Gpcr13, H218, LPB2, S1P2
- Ensembl
- ENSG00000267534
- RefSeq RNA
- NM_004230.4
- RefSeq protein
- NP_004221.3
This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. The encoded protein is a receptor for sphingosine 1-phosphate, which participates in cell proliferation, survival, and transcriptional activation. Defects in this gene have been associated with congenital profound deafness. [provided by RefSeq, Mar 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
sphingosine-1-phosphate receptor 2
- Symbol
- S1PR2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:10,221,433-10,231,331
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
7 sectionsContents
- Function
- Evolution
- [[Sequence homology|Paralogues]]
- See also
- References
- Further reading
- External links
Sphingosine-1-phosphate receptor 2, also known as S1PR2 or S1P2, is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P).
== Function ==
Excerpted from Wikipedia’s “S1PR2” article, available under the CC BY-SA 4.0 licence.