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SB357134
Sign in to saveAlso known as SB 357134, SB-357,134, SB-357134
SB-357134 is a drug which is used in scientific research. It acts as a potent, selective and orally active 5-HT6 receptor antagonist. SB-357134 and other 5-HT6 antagonists show nootropic effects in animal studies, and have been proposed as potential novel treatments for cognitive disorders such as schizophrenia and Alzheimer's disease.
Chemical data
- Formula
- C17H18Br2FN3O3S
- Molecular weight
- 523.2 g/mol
- IUPAC name
- N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
- SMILES
- COC1=C(C=C(C=C1)S(=O)(=O)NC2=C(C(=CC(=C2)Br)F)Br)N3CCNCC3
- InChIKey
- BLWHAZZXRHTFJE-UHFFFAOYSA-N
- XLogP
- 3.4
- Polar surface area
- 79.1 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 520.9419648560001
Show 3 more facts
- Commons category
- SB-357134
- chemical formula
- C₁₇H₁₈Br₂FN₃O₃S
- canonical SMILES
- COC1=C(C=C(C=C1)S(=O)(=O)NC2=CC(=CC(=C2Br)F)Br)N3CCNCC3
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
SB-357134 is a drug which is used in scientific research. It acts as a potent, selective and orally active 5-HT6 receptor antagonist. SB-357134 and other 5-HT6 antagonists show nootropic effects in animal studies, and have been proposed as potential novel treatments for cognitive disorders such as schizophrenia and Alzheimer's disease.
== References ==
Excerpted from Wikipedia’s “SB357134” article, available under the CC BY-SA 4.0 licence.