Structure via PubChem · Public domain (PubChem)
revospirone
Sign in to saveRevospirone (Bay Vq 7813) is an azapirone drug which was patented as a veterinary tranquilizer but was never marketed. It acts as a selective 5-HT1A receptor partial agonist. Similarly to other azapirones such as buspirone, revospirone produces 1-(2-pyrimidinyl)piperazine (1-PP) as an active metabolite. As a result, it also acts as an α2-adrenergic receptor antagonist to an extent.
Chemical data
- Formula
- C18H21N5O3S
- Molecular weight
- 387.5 g/mol
- IUPAC name
- 1,1-dioxo-2-[3-(4-pyrimidin-2-ylpiperazin-1-yl)propyl]-1,2-benzothiazol-3-one
- SMILES
- C1CN(CCN1CCCN2C(=O)C3=CC=CC=C3S2(=O)=O)C4=NC=CC=N4
- InChIKey
- MPLTZRTXQLNGED-UHFFFAOYSA-N
- XLogP
- 1.2
- Polar surface area
- 95.1 Ų
- H-bond donors
- 0
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 387.137
Show 3 more facts
- Commons category
- Revospirone
- chemical formula
- C₁₈H₂₁N₅O₃S
- canonical SMILES
- C1CN(CCN1CCCN2C(=O)C3=CC=CC=C3S2(=O)=O)C4=NC=CC=N4
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Revospirone (Bay Vq 7813) is an azapirone drug which was patented as a veterinary tranquilizer but was never marketed. It acts as a selective 5-HT1A receptor partial agonist. Similarly to other azapirones such as buspirone, revospirone produces 1-(2-pyrimidinyl)piperazine (1-PP) as an active metabolite. As a result, it also acts as an α2-adrenergic receptor antagonist to an extent.
==References==
Excerpted from Wikipedia’s “revospirone” article, available under the CC BY-SA 4.0 licence.