SOX4
Sign in to saveAlso known as EVI16, SRY-box 4, SRY-box transcription factor 4, CSS10
Transcription factor SOX-4 is a protein that in humans is encoded by the SOX4 gene.
Gene data
SOX4- Name
- SRY-box transcription factor 4
- Type
- protein-coding
- Aliases
- CSS10, EVI16, IDDSDF
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
SRY-box transcription factor 4
- Symbol
- SOX4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:21,593,751-21,598,619
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 2338
- exact match
- identifiers.org/ncbigene/6659
- genomic end
- 21598847
- genomic start
- 21593751
- cytogenetic location
- 6p22.3
via Wikidata · CC0
~1 min read
Article
7 sectionsContents
- Function
- Clinical significance
- Interactions
- See also
- References
- Further reading
- External links
Transcription factor SOX-4 is a protein that in humans is encoded by the SOX4 gene.
== Function ==