SIGLEC5

Also known as CD170, CD33L2, OB-BP2, OBBP2, SIGLEC-5, sialic acid binding Ig like lectin 5

Sialic acid-binding Ig-like lectin 5 is a protein that in humans is encoded by the SIGLEC5 gene. SIGLEC5 has also been designated CD170 (cluster of differentiation 170).

Gene data

SIGLEC5

Name: sialic acid binding Ig like lectin 5
Type: protein-coding
Aliases: CD170, CD33L2, OB-BP2, OBBP2, SIGLEC-5

This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012].

via MyGene.info

Gene · Ensembl

sialic acid binding Ig like lectin 5

Symbol: SIGLEC5
Biotype: Protein coding
Organism: Homo sapiens
Location: 19:51,610,948-51,630,401
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein SIGLEC5 PDB 2ZG1.png

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HomoloGene ID: 55783
exact match: identifiers.org/ncbigene/8778
genomic start: 51610960
genomic end: 51630401
cytogenetic location: 19q13.41

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Sialic acid-binding Ig-like lectin 5 is a protein that in humans is encoded by the SIGLEC5 gene. SIGLEC5 has also been designated CD170 (cluster of differentiation 170).

==References==