SLC38A1
Sign in to saveAlso known as ATA1, NAT2, SAT1, SNAT1, solute carrier family 38 member 1
Sodium-coupled neutral amino acid transporter 1 is a protein that in humans is encoded by the SLC38A1 gene.
Gene data
SLC38A1- Name
- solute carrier family 38 member 1
- Type
- protein-coding
- Position
- 46,183,054–46,270,070 (−)
- Aliases
- ATA1, NAT2, SAT1, SNAT1
- Ensembl
- ENSG00000111371
- RefSeq RNA
- NM_001077484.2, NM_001278387.2, NM_001278388.2, NM_001278389.2, NM_001278390.1
- RefSeq protein
- NP_001070952.1, NP_001265316.1, NP_001265317.1, NP_001265318.1, NP_001265319.1
Amino acid transporters play essential roles in the uptake of nutrients, production of energy, chemical metabolism, detoxification, and neurotransmitter cycling. SLC38A1 is an important transporter of glutamine, an intermediate in the detoxification of ammonia and the production of urea. Glutamine serves as a precursor for the synaptic transmitter, glutamate (Gu et al., 2001 [PubMed 11325958]).[supplied by OMIM, Mar 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
solute carrier family 38 member 1
- Symbol
- SLC38A1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:46,183,054-46,270,070
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 12745
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/81539
- genomic end
- 46663800
- genomic start
- 46576846
- chromosome
- human chromosome 12
- cytogenetic location
- 12q13.11
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Sodium-coupled neutral amino acid transporter 1 is a protein that in humans is encoded by the SLC38A1 gene.
Amino acid transporters play essential roles in the uptake of nutrients, production of energy, chemical metabolism, detoxification, and neurotransmitter cycling. SLC38A1 is an important transporter of glutamine, an intermediate in the detoxification of ammonia and the production of urea. Glutamine serves as a precursor for the synaptic transmitter, glutamate (Gu et al., 2001).[supplied by OMIM]
Excerpted from Wikipedia’s “SLC38A1” article, available under the CC BY-SA 4.0 licence.