Structural maintenance of chromosomes protein 6 is a protein that in humans is encoded by the SMC6 gene.
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Structural maintenance of chromosomes protein 6 is a protein that in humans is encoded by the SMC6 gene.
== Structure == The SMC6 was discovered first in fission yeast as RAD18 (SMC6). It forms a heterodimeric complex with Spr18 (SMC5) protein. In yeast, SMC5/6 complex has sub-units which consists of SMC5, SMC6 and six nonstructural maintenance of chromosomes (NSE) proteins. Nse1-Nse3-Nse4 subunits bridge the Smc5 head Smc6 and allow the binding of DNA.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).