SERPINB4
Sign in to saveAlso known as LEUPIN, PI11, SCCA-2, SCCA1, SCCA2, serpin family B member 4
Serpin B4 is a protein that in humans is encoded by the SERPINB4 gene.
Gene data
SERPINB4- Name
- serpin family B member 4
- Type
- protein-coding
- Aliases
- LEUPIN, PI11, SCCA-2, SCCA1, SCCA2
The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein is highly expressed in many tumor cells and can inactivate granzyme M, an enzyme that kills tumor cells. This protein, along with serpin B3, can be processed into smaller fragments that aggregate to form an autoantigen in psoriasis, probably by causing chronic inflammation. [provided by RefSeq, Jan 2017].
via MyGene.info
Gene · Ensembl
serpin family B member 4
- Symbol
- SERPINB4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 18:63,637,259-63,644,263
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 76659
- exact match
- identifiers.org/ncbigene/6318
- genomic end
- 63644256
- genomic start
- 61304493
- cytogenetic location
- 18q21.33
Sources (4)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- See also
- References
- Further reading
- External links
Serpin B4 is a protein that in humans is encoded by the SERPINB4 gene.
==See also== Serpin
Connections
Q180686
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human chromosome 18
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Ensembl genome database project
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protein
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gene
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chromosome
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digital object identifier
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bibcode
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human genome
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base pair
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locus
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gene expression
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angiotensins
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