STEAP3
Sign in to saveAlso known as AHMIO2, STMP3, TSAP6, dudlin-2, dudulin-2, pHyde, STEAP3 metalloreductase
Metalloreductase STEAP3 is an enzyme that in humans is encoded by the STEAP3 gene.
Gene data
STEAP3- Name
- STEAP3 metalloreductase
- Type
- protein-coding
- Aliases
- AHMIO2, STMP3, TSAP6, dudlin-2, dudulin-2, pHyde
This gene encodes a multipass membrane protein that functions as an iron transporter. The encoded protein can reduce both iron (Fe3+) and copper (Cu2+) cations. This protein may mediate downstream responses to p53, including promoting apoptosis. Deficiency in this gene can cause anemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015].
via MyGene.info
Wikidata facts
- Image
- Protein STEAP3 PDB 2VNS.png
Show 5 more facts
- HomoloGene ID
- 10084
- exact match
- identifiers.org/ncbigene/55240
- genomic end
- 120023228
- genomic start
- 119981384
- cytogenetic location
- 2q14.2
Sources (3)
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- Further reading
Metalloreductase STEAP3 is an enzyme that in humans is encoded by the STEAP3 gene.
STEAP3 is a metalloreductase, capable of converting iron from an insoluble ferric (Fe3+) to a soluble ferrous (Fe2+) form.