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GeneQ15333170· pop 5· linked from 47 articles

Also known as DAP1, GMP1, OFC10, PIC1, SENP2, SMT3, SMT3C, SMT3H3

Small ubiquitin-related modifier 1 is a protein that in humans is encoded by the SUMO1 gene.

Gene data

SUMO1
Name
small ubiquitin like modifier 1
Type
protein-coding
Position
202,206,171–202,238,604 (−)
Aliases
DAP1, GMP1, OFC10, PIC1, SMT3, SMT3C, SMT3H3, UBL1
RefSeq RNA
NM_001005781.2, NM_001005782.2, NM_001371392.1, NM_001371393.1, NM_001371394.1
RefSeq protein
NP_001005781.1, NP_001005782.1, NP_001358321.1, NP_001358322.1, NP_001358323.1

This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

small ubiquitin like modifier 1

Symbol
SUMO1
Biotype
Protein coding
Organism
Homo sapiens
Location
2:202,206,171-202,238,604
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Image
Protein SUMO1 PDB 1a5r.png
Show 8 more facts
HomoloGene ID
2514
genomic start
203070903
found in taxon
Homo sapiens
genomic end
203103331
Commons category
Small ubiquitin-related modifier proteins
cytogenetic location
2q33.1
Sources (4)

via Wikidata · CC0

~3 min read

Encyclopedic overview

8 sections
Contents
  • Function
  • Interactions
  • Role in the heart
  • As a drug target
  • See also
  • References
  • Further reading
  • External links

Small ubiquitin-related modifier 1 is a protein that in humans is encoded by the SUMO1 gene.

== Function ==

Excerpted from Wikipedia’s “SUMO1” article, available under the CC BY-SA 4.0 licence.

Available in 4 languages

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