suriclone

Suriclone (Suril) is a sedative and anxiolytic drug in the cyclopyrrolone family of drugs. Other cyclopyrrolone drugs include zopiclone and pagoclone.

Research

59 papers

Suriclone: a new anxiolytic drug.Progress in neuro-psychopharmacology & biological psychiatry · 1983
Anxiolytic cyclopyrrolones zopiclone and suriclone bind to a novel site linked allosterically to benzodiazepine receptors.Molecular pharmacology · 1984
Suriclone: a new cyclopyrrolone derivative recognizing receptors labeled by benzodiazepines in rat hippocampus and cerebellum.Journal of neurochemistry · 1983
Suriclone and diazepam in the treatment of neurotic anxiety. A double-blind cross-over trial.Psychopharmacology · 1987
Suriclone enhances the actions of chlorpromazine on human psychomotor performance but not on memory or plasma prolactin in healthy subjects.European journal of clinical pharmacology · 1994

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Wikidata facts

Mass: 477.07

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Commons category: Suriclone
chemical formula: C₂₀H₂₀ClN₅O₃S₂
canonical SMILES: CN1CCN(CC1)C(=O)OC2C3=C(C(=O)N2C4=NC5=C(C=C4)C=CC(=N5)Cl)SCCS3

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References

Suriclone (Suril) is a sedative and anxiolytic drug in the cyclopyrrolone family of drugs. Other cyclopyrrolone drugs include zopiclone and pagoclone.

Suriclone has a very similar pharmacological profile to the benzodiazepine family of drugs including sedative and anxiolytic properties but with less amnestic effects, and its chemical structure is quite different from that of the benzodiazepine drugs.