TACR1
Sign in to saveAlso known as NK1R, NKIR, SPR, TAC1R, tachykinin receptor 1
protein-coding gene in the species Homo sapiens
Gene data
TACR1- Name
- tachykinin receptor 1
- Type
- protein-coding
- Position
- 75,046,463–75,199,526 (−)
- Aliases
- NK1R, NKIR, SPR, TAC1R
- Ensembl
- ENSG00000115353
- RefSeq RNA
- NM_001058.4, NM_015727.3
- RefSeq protein
- NP_001049.1, NP_056542.1
This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. [provided by RefSeq, Sep 2008].
Gene Ontology
Biological process
aggressive behaviorpositive regulation of leukocyte migrationangiotensin-mediated drinking behaviorinflammatory responseG protein-coupled receptor signaling pathwayadenylate cyclase-activating G protein-coupled receptor signaling pathwayadenylate cyclase-activating G protein-coupled receptor signaling pathwayadenylate cyclase-activating G protein-coupled receptor signaling pathway
Molecular function
Pathways
Calcium signaling pathway - Homo sapiens (human)Neuroactive ligand-receptor interaction - Homo sapiens (human)Signal TransductionMembrane TraffickingSignaling by GPCRClass A/1 (Rhodopsin-like receptors)Peptide ligand-binding receptorsTachykinin receptors bind tachykininsGPCR downstream signallingG alpha (q) signalling events
via MyGene.info
Gene · Ensembl
tachykinin receptor 1
- Symbol
- TACR1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:75,046,463-75,199,526
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein TACR1 PDB 2KS9.png
Show 8 more facts
- HomoloGene ID
- 20288
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/6869
- genomic end
- 75199520
- genomic start
- 75273590
- chromosome
- human chromosome 2
- cytogenetic location
- 2p12
- expressed in
- vagina
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