TAS2R10
Sign in to saveAlso known as T2R10, TRB2, taste 2 receptor member 10
Taste receptor type 2 member 10 is a protein that in humans is encoded by the TAS2R10 gene. The protein is responsible for bitter taste recognition in mammals. It serves as a defense mechanism to prevent consumption of toxic substances which often have a characteristic bitter taste.
In the Vinony graph
Vinony's link graph records 487 inbound references to TAS2R10, and connects out to PubMed, Ensembl genome database project and calcium.
Vinony files it under Genes on human chromosome 12 and Human taste receptors.
Vinony links it to 5 Wikipedia language editions.
Gene data
TAS2R10- Name
- taste 2 receptor member 10
- Type
- protein-coding
- Position
- 10,825,219–10,826,358 (−)
- Aliases
- T2R10, TRB2
- Ensembl
- ENSG00000272805
- RefSeq RNA
- NM_023921.2
- RefSeq protein
- NP_076410.1
This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
taste 2 receptor member 10
- Symbol
- TAS2R10
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr HSCHR12_2_CTG2:24,023-25,064
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- exact match
- identifiers.org/ncbigene/50839
- found in taxon
- Homo sapiens
- HomoloGene ID
- 128355
- chromosome
- human chromosome 12
- genomic start
- 10977916
- genomic end
- 10978957
- cytogenetic location
- 12p13.2
- expressed in
- gastric mucosa
Sources (4)
via Wikidata · CC0
~5 min read
Encyclopedic overview
7 sectionsContents
- Function
- Structure
- Biological importance
- Therapeutic use
- See also
- References
- Further reading
Taste receptor type 2 member 10 is a protein that in humans is encoded by the TAS2R10 gene. The protein is responsible for bitter taste recognition in mammals. It serves as a defense mechanism to prevent consumption of toxic substances which often have a characteristic bitter taste.
== Function ==
Excerpted from Wikipedia’s “TAS2R10” article, available under the CC BY-SA 4.0 licence.