temocillin
Sign in to saveTemocillin is a β-lactamase-resistant penicillin introduced by Beecham, marketed by Eumedica Pharmaceuticals as Negaban. It is used primarily for the treatment of multiple drug-resistant, Gram-negative bacteria. It is actually a 6-methoxy Ticarcillin; it is also a carboxypenicillin.
Chemical data
- Formula
- C16H18N2O7S2
- Molecular weight
- 414.5 g/mol
- IUPAC name
- (2S,5R,6S)-6-[(2-carboxy-2-thiophen-3-ylacetyl)amino]-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- +414.056
Show 1 more fact
- P2868
- antibiotic
via Wikidata · CC0
Article
6 sectionsContents
- Pharmacology
- Dosage
- Adverse effects
- Synthesis
- References
- Further reading
Temocillin is a β-lactamase-resistant penicillin introduced by Beecham, marketed by Eumedica Pharmaceuticals as Negaban. It is used primarily for the treatment of multiple drug-resistant, Gram-negative bacteria. It is actually a 6-methoxy Ticarcillin; it is also a carboxypenicillin.
==Pharmacology== Temocillin is a β-lactamase-resistant penicillin. It is not active against Gram-positive bacteria or bacteria with altered penicillin-binding proteins.