terlipressin
Sign in to saveAlso known as SID124896640, Terlipressine, H-Gly-Gly-Gly-Cys(1)-Tyr-Phe-Gln-Asn-Cys(1)-Pro-Lys-Gly-NH2
Terlipressin, sold under the brand name Terlivaz among others, is an analogue of vasopressin used as a vasoactive drug in the management of low blood pressure. It has been found to be effective when norepinephrine does not help. Terlipressin is a vasopressin receptor agonist.
Key facts
- Drug.verifiedrevid
- 470602469
- Drug.image
- terlipressin.png
- Drug.image_class
- skin-invert-image
- Drug.tradename
- Terlivaz
- Drug.routes_of_administration
- Intravenous
- Drug.ATC_prefix
- H01
- Drug.ATC_suffix
- BA04
- Drug.legal_US
- Rx-only
- Drug.protein_bound
- ~30%
- Drug.CAS_number
- 14636-12-5
- Drug.PubChem
- 72081
- Drug.DrugBank
- DB02638
- Drug.ChemSpiderID
- 65067
- Drug.UNII
- 7Z5X49W53P
- Drug.KEGG
- D06672
- Drug.IUPAC_name
- 1-{[(4R,7S,10S,13S,16S,19R)-19-{[({[(aminoacetyl)amino]acetyl}amino)acetyl]amino}-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-N-(2-amino-2-oxoethyl)-L-lysinamide
- Drug.C
- 52
- Drug.H
- 74
via Wikipedia infobox
Research
1,380 papers- Terlipressin plus Albumin for the Treatment of Type 1 Hepatorenal Syndrome.The New England journal of medicine · 2021
- Terlipressin for hepatorenal syndrome.Current opinion in gastroenterology · 2024
- Terlipressin in the management of liver disease.Expert opinion on pharmacotherapy · 2023
- Terlipressin given by continuous intravenous infusion versus intravenous boluses in the treatment of hepatorenal syndrome: A randomized controlled study.Hepatology (Baltimore, Md.) · 2016
- Terlipressin Acetate.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2023
via PubMed
~4 min read
Encyclopedic overview
5 sectionsContents
- Medical uses
- Contraindications
- Society and culture
- References
- External links
{{Infobox drug | verifiedrevid = 470602469 | image = terlipressin.png | image_class = skin-invert-image | alt =
| tradename = Terlivaz | Drugs.com = | pregnancy_category = | routes_of_administration = Intravenous | ATC_prefix = H01 | ATC_suffix = BA04 | ATC_supplemental =
Excerpted from Wikipedia’s “terlipressin” article, available under the CC BY-SA 4.0 licence.