OXTR
Sign in to saveAlso known as OT-R, oxytocin receptor
protein-coding gene in the species Homo sapiens
Gene data
OXTR- Name
- oxytocin receptor
- Type
- protein-coding
- Position
- 8,750,381–8,769,628 (−)
- Aliases
- OT-R, OTR
- Ensembl
- ENSG00000180914
- RefSeq RNA
- NM_000916.4, NM_001354653.2, NM_001354654.2, NM_001354655.2, NM_001354656.3
- RefSeq protein
- NP_000907.2, NP_001341582.1, NP_001341583.1, NP_001341584.1, NP_001341585.1
The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
muscle contractioncell surface receptor signaling pathwayG protein-coupled receptor signaling pathwayG protein-coupled receptor signaling pathwayadenylate cyclase-inhibiting G protein-coupled receptor signaling pathwayphospholipase C-activating G protein-coupled receptor signaling pathwaypositive regulation of cytosolic calcium ion concentrationfemale pregnancy
Molecular function
Pathways
Calcium signaling pathway - Homo sapiens (human)cAMP signaling pathway - Homo sapiens (human)Neuroactive ligand-receptor interaction - Homo sapiens (human)Oxytocin signaling pathway - Homo sapiens (human)Signal TransductionSignaling by GPCRClass A/1 (Rhodopsin-like receptors)Peptide ligand-binding receptorsGPCR downstream signallingVasopressin-like receptors
via MyGene.info
Gene · Ensembl
oxytocin receptor
- Symbol
- OXTR
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:8,750,381-8,769,628
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI