English
relcovaptan
Sign in to saveAlso known as SR 49059, SR-49059, SR49059
Relcovaptan (SR-49059) is a non-peptide vasopressin receptor antagonist, selective for the V1A subtype. It has shown positive initial results for the treatment of Raynaud syndrome and dysmenorrhoea, and as a tocolytic, although it is not yet approved for clinical use.
Research
118 papers- Vasopressin antagonists.Cellular and molecular life sciences : CMLS · 2006
- Relcovaptan: a promising therapeutic agent in traumatic spinal cord injury that acts by modulating newly identified transcriptional regulators of aquaporins compared to tolvaptan.Turkish journal of medical sciences · 2025
- Non-peptide arginine-vasopressin antagonists: the vaptans.Lancet (London, England) · 2008
- Bryophyllum pinnatum Inhibits Oxytocin and Vasopressin Signaling in Myometrial Cells.Planta medica · 2024
- The effect of relcovaptan (SR 49059), an orally active vasopressin V1a receptor antagonist, on uterine contractions in preterm labor.Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2005
via PubMed
Wikidata facts
- Mass
- 619.094677
Show 3 more facts
- chemical formula
- C₂₈H₂₇Cl₂N₃O₇S
- isomeric SMILES
- COC1=C(C=C(C=C1)S(=O)(=O)N2[C@H]([C@](C3=C2C=CC(=C3)Cl)(C4=CC=CC=C4Cl)O)C(=O)N5CCC[C@H]5C(=O)N)OC
- canonical SMILES
- COC1=C(C=C(C=C1)S(=O)(=O)N2C(C(C3=C2C=CC(=C3)Cl)(C4=CC=CC=C4Cl)O)C(=O)N5CCCC5C(=O)N)OC
Sources (2)
via Wikidata · CC0
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Article
1 sectionsContents
- References
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