terutroban
Sign in to saveAlso known as S 18886, S18886, triplion
Terutroban is an antiplatelet agent developed by Servier Laboratories. It is a selective thromboxane prostanoid (TP) antagonist and is an orally active drug in clinical development for the secondary prevention of acute thrombotic complications.
~3 min read
Encyclopedic overview
2 sectionsContents
- Method of action
- References
{{drugbox | Verifiedfields = changed | Watchedfields = changed | UNII_Ref = | UNII = A6WX9391D8 | verifiedrevid = 407704475 | IUPAC_name = 3-((6R)-6-{[(4-Chlorophenyl)sulfonyl]amido}-2-methyl-5,6,7,8-tetrahydronaphthalen-1-yl]propanoic acid | image = Terutroban acid skeletal.svg | image_class = skin-invert-image | CAS_number_Ref = | CAS_number = 165538-40-9 | CAS_supplemental = (sodium salt) | ATC_prefix = none | ATC_suffix = | ATC_supplemental = | PubChem = 9938840 | ChemSpiderID_Ref = | ChemSpiderID = 8114465 | StdInChI_Ref = | StdInChI = 1S/C20H22ClNO4S/c1-13-2-3-14-12-16(6-9-19(14)18(13)10-11-20(23)24)22-27(25,26)17-7-4-15(21)5-8-17/h2-5,7-8,16,22H,6,9-12H2,1H3,(H,23,24)/t16-/m1/s1 | StdInChIKey_Ref = | StdInChIKey = HWEOXFSBSQIWSY-MRXNPFEDSA-N | DrugBank_Ref = | DrugBank = | chemical_formula = | C=20 | H=22 | Cl=1 | N=1 | O=4 | S=1 | smiles = CC1=C(C2=C(CC(CC2)NS(=O)(=O)C3=CC=C(C=C3)Cl)C=C1)CCC(=O)O | bioavailability = | protein_bound = | metabolism = | elimination_half-life = 6–10 hours | excretion = | pregnancy_AU = | pregnancy_US = | pregnancy_category= | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = Investigational | routes_of_administration = Oral }}
Terutroban is an antiplatelet agent developed by Servier Laboratories. It is a selective thromboxane prostanoid (TP) antagonist and is an orally active drug in clinical development for the secondary prevention of acute thrombotic complications.
Excerpted from Wikipedia’s “terutroban” article, available under the CC BY-SA 4.0 licence.