Structure via PubChem · Public domain (PubChem)
theodrenaline
Sign in to saveTheodrenaline (), also known as noradrenalinoethyltheophylline or as noradrenaline theophylline, is a chemical linkage of norepinephrine (noradrenaline) and theophylline used as a cardiac stimulant. It is sometimes combined with cafedrine.
Chemical data
- Formula
- C17H21N5O5
- Molecular weight
- 375.4 g/mol
- IUPAC name
- 7-[2-[[2-(3,4-dihydroxyphenyl)-2-hydroxyethyl]amino]ethyl]-1,3-dimethylpurine-2,6-dione
- SMILES
- CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CCNCC(C3=CC(=C(C=C3)O)O)O
- InChIKey
- WMCMJIGLYZDKRN-UHFFFAOYSA-N
- XLogP
- -0.8
- Polar surface area
- 131 Ų
- H-bond donors
- 4
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- cardiovascular disease
via ChEMBL · EBI
Research
51 papers- Cafedrine/Theodrenaline (20:1) Is an Established Alternative for the Management of Arterial Hypotension in Germany-a Review Based on a Systematic Literature Search.Frontiers in pharmacology · 2017
- [Drug interaction between ceftriaxone and theodrenaline/cafedrine : A case example].Die Anaesthesiologie · 2023
- Reporting dinaciclib and theodrenaline as a multitargeted inhibitor against SARS-CoV-2: an in-silico study.Journal of biomolecular structure & dynamics · 2023
- Phenylephrine versus cafedrine/theodrenaline (Akrinor) for the treatment of spinal anaesthesia-induced maternal hypotension during caesarean section: a retrospective single-centre cohort study.BMJ open · 2022
- Cafedrine/theodrenaline in anaesthesia: influencing factors in restoring arterial blood pressure.Der Anaesthesist · 2015
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 375.154
Show 3 more facts
- chemical formula
- C₁₇H₂₁N₅O₅
- canonical SMILES
- CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CCNCC(C3=CC(=C(C=C3)O)O)O
- subject has role
- antihypertensive drug
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
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Excerpted from Wikipedia’s “theodrenaline” article, available under the CC BY-SA 4.0 licence.