theophylline
Sign in to savethumb|right|upright|Theophylline extended-release tablets in Japan Theophylline, also known as 1,3-dimethylxanthine, is a drug that inhibits phosphodiesterase and blocks adenosine receptors. It is used to treat chronic obstructive pulmonary disease (COPD) and asthma. Its pharmacology is similar to other methylxanthine drugs (e.g., theobromine and caffeine). Trace amounts of theophylline are naturally present in tea, coffee, chocolate, yerba mate, guarana, and kola nut.
Key facts
- Drug.legal_AU
- S4
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 470606142
- Drug.IUPAC_name
- 1,3-dimethyl-7H-purine-2,6-dione
- Drug.image
- Theophylline.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 150
- Drug.image2
- Theophylline 3D ball.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 180
- Drug.tradename
- Theolair, Slo-Bid
- Drug.MedlinePlus
- a681006
- Drug.pregnancy_AU
- A
- Drug.pregnancy_US
- C
- Drug.legal_CA
- Rx-only
- Drug.legal_UK
- P
- Drug.legal_US
- Rx-only
- Drug.routes_of_administration
- By mouth, intravenous, rectal
via Wikipedia infobox
Article
21 sectionsContents
- Medical uses
- Performance enhancement in sports
- Adverse effects
- Interactions
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Distribution
- Metabolism
- Excretion
- Spectroscopy
- UV-visible
- Proton NMR
- <sup>13</sup>C-NMR
- Natural occurrences
- Crystalline forms in solid state
- History
- Etymology
- See also
- References
- External links
thumb|right|upright|Theophylline extended-release tablets in Japan Theophylline, also known as 1,3-dimethylxanthine, is a drug that inhibits phosphodiesterase and blocks adenosine receptors. It is used to treat chronic obstructive pulmonary disease (COPD) and asthma. Its pharmacology is similar to other methylxanthine drugs (e.g., theobromine and caffeine). Trace amounts of theophylline are naturally present in tea, coffee, chocolate, yerba mate, guarana, and kola nut.
== Medical uses == The main actions of theophylline involve: relaxing bronchial smooth muscle increasing heart muscle contractility and efficiency (positive inotrope) increasing heart rate (positive chronotropic) increasing blood pressure increasing renal blood flow anti-inflammatory effects central nervous system stimulatory effect, mainly on the medullary respiratory center
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Adenosine receptor antagonistsBitter compoundsBronchodilatorsDrugboxes which contain changes to watched fieldsDrugs developed by MerckECHA InfoCard ID from WikidataHistone Acetyltransferase InhibitorHuman drug metabolitesPhosphodiesterase inhibitorsPro-motivational agentsRecreational drug metabolitesWakefulness-promoting agents