dyphylline
Sign in to saveAlso known as 7-(2,3-dihydroxypropyl)theophylline, 7-(2,3-dihydroxypropyl)-1,3-dimethylxanthine, 1,3-dimethyl-7-(2,3-dihydroxypropyl)xanthine, diprophylline, (±)-diprophylline, 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione, (±)-dyphylline, dihydroxypropyl theopylin
Diprophylline (INN) or dyphylline (USAN) (trade names Dilor, Lufyllin) is a xanthine derivative with bronchodilator and vasodilator effects. It is used in the treatment of respiratory disorders like asthma, cardiac dyspnea, and bronchitis. It acts as an adenosine receptor antagonist and phosphodiesterase inhibitor.
Research
221 papers- Dyphylline.2006
- Repurposing dyphylline as a pan-coronavirus antiviral therapy.Future medicinal chemistry · 2022
- Liver Injury Associated with Turmeric-A Growing Problem: Ten Cases from the Drug-Induced Liver Injury Network [DILIN].The American journal of medicine · 2023
- Bioavailability of dyphylline and dyphylline-guaifenesin tablets in humans.Journal of pharmaceutical sciences · 1985
- Theophylline derivatives promote primordial follicle activation via cAMP-PI3K/Akt pathway and ameliorate fertility deficits in naturally aged mice.International journal of biological sciences · 2024
via PubMed
Wikidata facts
- Mass
- 254.101505
Show 8 more facts
- found in taxon
- Haplophyllum tuberculatum
- has characteristic
- bitterness
- Commons category
- Diprophylline
- chemical formula
- C₁₀H₁₄N₄O₄
- World Health Organisation international non-proprietary name
- diprophylline
- canonical SMILES
- CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC(CO)O
- subject has role
- bronchodilator
- medical condition treated
- pulmonary emphysema
Sources (5)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Diprophylline (INN) or dyphylline (USAN) (trade names Dilor, Lufyllin) is a xanthine derivative with bronchodilator and vasodilator effects. It is used in the treatment of respiratory disorders like asthma, cardiac dyspnea, and bronchitis. It acts as an adenosine receptor antagonist and phosphodiesterase inhibitor.
== See also == Xanthine
Excerpted from Wikipedia’s “dyphylline” article, available under the CC BY-SA 4.0 licence.
Available in 9 languages
via Wikidata sitelinks · CC0