File:Thymin.svg · Wikimedia Commons · See Wikimedia Commons
تیمین
Sign in to saveAlso known as 5-methylpyrimidine-2,4(1H,3H)-dione, 2,4-dihydroxy-5-methylpyrimidine, 5-methyl-2,4(1H,3H)-pyrimidinedione, 5-methyluracil, Thymin, 2,4(1H,3H)-Pyrimidinedione, 5-methyl-, 5-Methyl-2,4-dihydroxypyrimidine, 5-Methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
Thymine () (symbol T or Thy) is one of the four nucleotide bases in the nucleic acid of DNA that are represented by the letters G–C–A–T. The others are adenine, guanine, and cytosine. Thymine is also known as 5-methyluracil, a pyrimidine nucleobase. In RNA, thymine is replaced by the nucleobase uracil. Thymine was first isolated in 1893 by Albrecht Kossel and Albert Neumann from calf thymus glands, hence its name.
OverviewAI-generated
Thymine is a chemical compound with the IUPAC name 5-methyl-1H-pyrimidine-2,4-dione. Its chemical formula is C₅H₆N₂O₂, and it has a mass of 126.043. The substance features a melting point of 317. In terms of molecular properties, thymine has a charge of 0, an xlogp value of -0.6, and a topological polar surface area of 58.2. It contains two hydrogen bond donors and two hydrogen bond acceptors.
The compound is associated with a weight of 126.11. Its canonical SMILES notation is CC1=CNC(=O)NC1=O. Thymine is referenced by 566 other encyclopedia articles. Additionally, there are 18572 PubMed entries associated with the query for thymine.
Synthesized by Vinony from 18 facts across 4 sources: Wikidata, PubChem, PubMed, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Chemical data
- Formula
- C5H6N2O2
- Molecular weight
- 126.11 g/mol
- IUPAC name
- 5-methyl-1H-pyrimidine-2,4-dione
- SMILES
- CC1=CNC(=O)NC1=O
- InChIKey
- RWQNBRDOKXIBIV-UHFFFAOYSA-N
- XLogP
- -0.6
- Polar surface area
- 58.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Research
18,572 papers- Thymine methyls and DNA-protein interactions.ReviewNucleic acids research · 1987Ivarie RDOI: 10.1093/nar/15.23.9975
- A new method for sequencing DNA.Proceedings of the National Academy of Sciences of the United States of America · 1977Maxam AM, Gilbert WDOI: 10.1073/pnas.74.2.560
- Thymine-Modified Silicones: A Bioinspired Approach to Cross-Linked, Recyclable Silicone Polymers.Biomacromolecules · 2023Voigt LJ, Tucker KE, Zelisko PMDOI: 10.1021/acs.biomac.3c00185
- Thymine dissociation and dimer formation: A Raman and synchronous fluorescence spectroscopic study.Proceedings of the National Academy of Sciences of the United States of America · 2021Nagpal A, Dhankhar D, Cesario TC et al.DOI: 10.1073/pnas.2025263118
- The Radiation Stability of Thymine in Solid H(2)O.Astrobiology · 2020Materese CK, Gerakines PA, Hudson RLDOI: 10.1089/ast.2019.2199
- Photocrosslinking Probes Proximity of Thymine Modifiers Tethering Excitonically Coupled Dye Aggregates to DNA Holliday Junction.Molecules (Basel, Switzerland) · 2022Basu S, Cervantes-Salguero K, Yurke B et al.DOI: 10.3390/molecules27134006
- [Thymine dimerization and survival of bacteria].Journal of molecular biology · 1962WACKER A, DELLWEG H, JACHERTS DDOI: 10.1016/s0022-2836(62)80022-9
- Thymine and thymidine synthesis.Biochimica et biophysica acta · 1956BARNER HD, COHEN SS, GREEN MDOI: 10.1016/0006-3002(56)90252-9
via PubMed
Gallery (7)
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