tymina

Also known as 5-methylpyrimidine-2,4(1H,3H)-dione, 2,4-dihydroxy-5-methylpyrimidine, 5-methyl-2,4(1H,3H)-pyrimidinedione, 5-methyluracil, Thymin, 2,4(1H,3H)-Pyrimidinedione, 5-methyl-, 5-Methyl-2,4-dihydroxypyrimidine, 5-Methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

związek chemiczny

OverviewAI-generated

Thymine is a chemical compound with the IUPAC name 5-methyl-1H-pyrimidine-2,4-dione. Its chemical formula is C₅H₆N₂O₂, and it has a mass of 126.043. The substance features a melting point of 317. In terms of molecular properties, thymine has a charge of 0, an xlogp value of -0.6, and a topological polar surface area of 58.2. It contains two hydrogen bond donors and two hydrogen bond acceptors.

The compound is associated with a weight of 126.11. Its canonical SMILES notation is CC1=CNC(=O)NC1=O. Thymine is referenced by 566 other encyclopedia articles. Additionally, there are 18572 PubMed entries associated with the query for thymine.

Synthesized by Vinony from 18 facts across 4 sources: Wikidata, PubChem, PubMed, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.

In the Vinony graph

Within Vinony's link graph, tymina is referenced by 566 other articles, and connects out to nucleotide base, deoxythymidine and deoxyribonucleotide.

It is catalogued under topics including Acylureas, Chembox image size set and ECHA InfoCard ID from Wikidata.

Its subject is documented across 66 Wikipedia language editions.

Chemical data

Formula: C5H6N2O2
Molecular weight: 126.11 g/mol
IUPAC name: 5-methyl-1H-pyrimidine-2,4-dione
SMILES: CC1=CNC(=O)NC1=O
InChIKey: RWQNBRDOKXIBIV-UHFFFAOYSA-N
XLogP: -0.6
Polar surface area: 58.2 Å²
H-bond donors: 2
H-bond acceptors: 2
Formal charge: 0

via PubChem

Drug data · ChEMBL

Molecule type: Small molecule

via ChEMBL · EBI

Research

18,572 papers

Thymine methyls and DNA-protein interactions.ReviewNucleic acids research · 1987Ivarie RDOI: 10.1093/nar/15.23.9975
A new method for sequencing DNA.Proceedings of the National Academy of Sciences of the United States of America · 1977Maxam AM, Gilbert WDOI: 10.1073/pnas.74.2.560
Thymine-Modified Silicones: A Bioinspired Approach to Cross-Linked, Recyclable Silicone Polymers.Biomacromolecules · 2023Voigt LJ, Tucker KE, Zelisko PMDOI: 10.1021/acs.biomac.3c00185
Thymine dissociation and dimer formation: A Raman and synchronous fluorescence spectroscopic study.Proceedings of the National Academy of Sciences of the United States of America · 2021Nagpal A, Dhankhar D, Cesario TC et al.DOI: 10.1073/pnas.2025263118
The Radiation Stability of Thymine in Solid H(2)O.Astrobiology · 2020Materese CK, Gerakines PA, Hudson RLDOI: 10.1089/ast.2019.2199
Photocrosslinking Probes Proximity of Thymine Modifiers Tethering Excitonically Coupled Dye Aggregates to DNA Holliday Junction.Molecules (Basel, Switzerland) · 2022Basu S, Cervantes-Salguero K, Yurke B et al.DOI: 10.3390/molecules27134006
[Thymine dimerization and survival of bacteria].Journal of molecular biology · 1962WACKER A, DELLWEG H, JACHERTS DDOI: 10.1016/s0022-2836(62)80022-9
Thymine and thymidine synthesis.Biochimica et biophysica acta · 1956BARNER HD, COHEN SS, GREEN MDOI: 10.1016/0006-3002(56)90252-9

via PubMed

Wikidata facts

Has part: hydrogen
Mass: 126.043

Show 6 more facts

canonical SMILES: CC1=CNC(=O)NC1=O
chemical formula: C₅H₆N₂O₂
found in taxon: Habenaria digitata
Commons category: Thymine
melting point: 317
subject has role: primary metabolite

Sources (6)

via Wikidata · CC0

Article · Polski

Tymina – organiczny związek chemiczny, należący do zasad pirymidynowych. Jest ważnym składnikiem DNA. Tymina (T) łączy się z adeniną (A) w DNA, a w RNA zastąpiona jest uracylem (U). Tymina po połączeniu z deoksyrybozą tworzy nukleozyd pirymidynowy - tymidynę, natomiast po przyłączeniu reszt fosforowych tworzy , TDP i .

Abstract from DBpedia / Wikipedia · CC BY-SA